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EDNRB Rabbit anti-Bovine, Dog, Goat, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89127905 Shop All Abnova Corporation Products
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50 μg
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89-127-905 50 μg
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Catalog No. 89-127-905 Supplier Abnova Corporation Supplier No. PAB26265
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Description

Rabbit polyclonal antibody raised against synthetic peptide of EDNRB.

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq

Specifications

Antigen EDNRB
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of EDNRB.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene EDNRB
Gene Accession No. P24530
Gene Alias ABCDS/ETB/ETBR/ETRB/HSCR/HSCR2
Gene Symbols EDNRB
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 19 amino acid at C-terminus of human EDNRB.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1910
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Bovine, Canine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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