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EDNRB Rabbit anti-Bovine, Dog, Goat, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of EDNRB.

Manufacturer:  Abnova Corporation PAB26265

Catalog No. 89-127-905


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Description

Description

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq

Specifications

Specifications

EDNRB
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8 ug/mL) The optimal working dilution should be determined by the end user.
EDNRB
Liquid
EDNRB
A synthetic peptide corresponding to 19 amino acid at C-terminus of human EDNRB.
50 ug
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry (PFA fixed)
Rabbit polyclonal antibody raised against synthetic peptide of EDNRB.
In PBS (0.09% sodium azide)
P24530
ABCDS|ETB|ETBR|ETRB|HSCR|HSCR2
Rabbit
Immunoaffinity chromatography
RUO
Primary
1910
Bovine, Canine, Goat, Hamster, Human, Monkey, Murine, Porcine, Rabbit, Rat
SDS
Documents
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