EGFR (phospho Y1197), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of EGFR.

Supplier:  Abnova Corporation PAB10009

Catalog No. 89-114-550

Description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq

Specifications

• Antigen: EGFR
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of EGFR.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene Accession No.: P00533;NP_005219
• Gene Symbols: EGFR
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Y1197 of human EGFR.
• Regulatory Status: RUO
• Gene ID (Entrez): 1956
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:4000-1:20000) Western Blot (1:250-1:1500) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: EGFR
• Gene Alias: ERBB/ERBB1/HER1/PIG61/mENA
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Reactivity occurs against human EGFR pY1197 protein and This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human EGFR is minimal by ELISA.
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only