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Description
The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | EHMT1 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of EHMT1. |
| Dilution | Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | EHMT1 |
| Gene Accession No. | NP_079033;Q9H9B1 |
| Gene Alias | DEL9q34/DKFZp667M072/EUHMTASE1/Eu-HMTase1/FLJ12879/FP13812/GLP/KIAA1876/KMT1D/bA188C12.1 |
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