EIF2S1 (phospho S51), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-490	100 μg

Catalog No. 89-127-490 Supplier Abnova Corporation Supplier No. PAB25861

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of EIF2S1.

The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36kDa), beta (38kDa, MIM 603908), and gamma (52kDa, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM

Sequence: E-L-Sp-R-R

Specifications

• Antigen: EIF2S1
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of EIF2S1.
• Dilution: Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: EIF2S1
• Gene Accession No.: P05198
• Gene Alias: EIF-2/EIF-2A/EIF-2alpha/EIF2/EIF2A
• Gene Symbols: EIF2S1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S51 of human EIF2S1.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1965
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only