EIF2S1 (phospho S49), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of EIF2S1.

Supplier:  Abnova Corporation PAB25902

Catalog No. 89-127-532

Description

The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36kDa), beta (38kDa, MIM 603908), and gamma (52kDa, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM

Sequence: L-L-Sp-E-L

Specifications

• Antigen: EIF2S1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user.
• Gene: EIF2S1
• Gene Alias: EIF-2/EIF-2A/EIF-2alpha/EIF2/EIF2A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1965
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed)
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of EIF2S1.
• Formulation: In PBS (without mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: P05198
• Gene Symbols: EIF2S1
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S49 of human EIF2S1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only