EIF4EBP1 (phospho T70), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-668	100 μL

Catalog No. 89-130-668 Supplier Abnova Corporation Supplier No. PAB29233

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human EIF4EBP1.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]

Specifications

• Antigen: EIF4EBP1
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human EIF4EBP1.
• Dilution: Immunohistochemistry (1:50-1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (without mg²⁺ and Ca²⁺), (50% glycerol, 0.02% sodium azide)
• Gene: EIF4EBP1
• Gene Accession No.: Q13541
• Gene Alias: 4E-BP1/4EBP1/BP-1/MGC4316/PHAS-I
• Gene Symbols: EIF4EBP1
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T70 of human EIF4EBP1.
• Purification Method: Affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1978
• Test Specificity: This antibody detects endogenous levels of EIF4EBP1 only when phosphorylated at threonine 70.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only