EIF4EBP1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of EIF4EBP1.

Supplier:  Abnova Corporation PAB3954

Catalog No. 89-131-219

Description

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]

Specifications

• Antigen: EIF4EBP1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of EIF4EBP1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_004086
• Gene Symbols: EIF4EBP1
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding T69 of human EIF4EBP1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-50) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene: EIF4EBP1
• Gene Alias: 4E-BP1/4EBP1/BP-1/MGC4316/PHAS-I
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 1978
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only