EIF4EBP1 (phospho S65), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of EIF4EBP1.

Supplier:  Abnova Corporation PAB16946

Catalog No. 89-118-749

Description

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]

Specifications

• Antigen: EIF4EBP1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of EIF4EBP1.
• Formulation: In 20mM PBS, 0.15M NaCl, pH 7.2 (0.01% sodium azide)
• Gene Accession No.: Q13541
• Gene Symbols: EIF4EBP1
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S65 of human EIF4EBP1.
• Regulatory Status: RUO
• Gene ID (Entrez): 1978
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user.
• Gene: EIF4EBP1
• Gene Alias: 4E-BP1/4EBP1/BP-1/MGC4316/PHAS-I
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of 4EBP1 only when phosphorylated at serine 65.
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only