EP300 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-520	100 μL

Catalog No. 89-126-520 Supplier Abnova Corporation Supplier No. PAB24848

Description

Rabbit polyclonal antibody raised against synthetic peptide of EP300.

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq

Specifications

• Antigen: EP300
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of EP300.
• Dilution: Western Blot (1:500-1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In 1X PBS, pH 7.2 (0.05% sodium azide)
• Gene: EP300
• Gene Alias: KAT3B/p300
• Gene Symbols: EP300
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to EP300.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2033
• Test Specificity: EP300 polyclonal antibody detects endogenous levels of EP300 protein.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only