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ERBB4 (phospho Y1162), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114248 Shop All Abnova Corporation Products
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400 μL
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89-114-248 400 μL
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Catalog No. 89-114-248 Supplier Abnova Corporation Supplier No. PAB0486
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ERBB4.

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq

Specifications

Antigen ERBB4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of ERBB4.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene ERBB4
Gene Accession No. NP_005226;Q15303
Gene Alias HER4/MGC138404/p180erbB4
Gene Symbols ERBB4
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1162 of human ERBB4.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2066
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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