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Description
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6)
Specifications
Specifications
| Antigen | ERCC4 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of ERCC4. |
| Dilution | Western Blot (1:500-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol) |
| Gene | ERCC4 |
| Gene Accession No. | Q92889 |
| Gene Alias | RAD1/XPF |
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