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ESPL1 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89119708 Shop All Abnova Corporation Products
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100 μg
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89-119-708 100 μg
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Catalog No. 89-119-708 Supplier Abnova Corporation Supplier No. PAB18135
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Description

Rabbit polyclonal antibody raised against synthetic peptide of ESPL1.

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 604359) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM

Specifications

Antigen ESPL1
Applications ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of ESPL1.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) Immunofluorescence (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene ESPL1
Gene Accession No. Q14674
Gene Alias ESP1/FLJ46492/KIAA0165/SEPARASE/SEPARIN
Gene Symbols ESPL1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human ESPL1.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9700
Test Specificity This antibody is specific to ESPL1.
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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