ESR1 Rabbit anti-Bovine, Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-120-363	100 μg

Catalog No. 89-120-363 Supplier Abnova Corporation Supplier No. PAB18805

Description

Rabbit polyclonal antibody raised against synthetic peptide of ESR1.

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]

Specifications

• Antigen: ESR1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of ESR1.
• Dilution: ELISA (1:160000) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In buffer containing 0.02% sodium azide
• Gene: ESR1
• Gene Accession No.: P03372
• Gene Alias: DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1
• Gene Symbols: ESR1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to residues surrounding amino acid 254 of human ESR1.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2099
• Target Species: Bovine, Human, Mouse, Rat
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only