F7, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-403	150 μg

Catalog No. 89-121-403 Supplier Abnova Corporation Supplier No. PAB19890

Description

Rabbit polyclonal antibody raised against native F7.

This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq

Specifications

• Antigen: F7
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against native F7.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.5 (0.02% sodium azide, 50% glycerol (v/v))
• Gene: F7
• Gene Symbols: F7
• Host Species: Rabbit
• Immunogen: Native purified F7 from human plasma.
• Purification Method: Affinity purification
• Quantity: 150 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2155
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only