FADD Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-070	100 μg

Catalog No. 89-121-070 Supplier Abnova Corporation Supplier No. PAB19541

Description

Rabbit polyclonal antibody raised against synthetic peptide of FADD.

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq

Specifications

• Antigen: FADD
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of FADD.
• Dilution: Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 0.9mg NaCl, 0.2mg Na₂HPO₄ (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
• Gene: FADD
• Gene Alias: GIG3/MGC8528/MORT1
• Gene Symbols: FADD
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human FADD.
• Purification Method: Immunoaffinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8772
• Target Species: Human
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG

For Research Use Only