FADD Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-119-725	100 μg

Catalog No. 89-119-725 Supplier Abnova Corporation Supplier No. PAB18152

Description

Rabbit polyclonal antibody raised against synthetic peptide of FADD.

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq

Specifications

• Antigen: FADD
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of FADD.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: FADD
• Gene Accession No.: Q13158
• Gene Alias: GIG3/MGC8528/MORT1
• Gene Symbols: FADD
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to human FADD.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8772
• Test Specificity: This antibody is specific to FADD.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only