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FANCA Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89119986 Shop All Abnova Corporation Products
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100 μg
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89-119-986 100 μg
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Catalog No. 89-119-986 Supplier Abnova Corporation Supplier No. PAB18424
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Description

Rabbit polyclonal antibody raised against synthetic peptide of FANCA.

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq

Specifications

Antigen FANCA
Applications ELISA, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of FANCA.
Dilution Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene FANCA
Gene Accession No. O15360
Gene Alias FA/FA-H/FA1/FAA/FACA/FAH/FANCH/MGC75158
Gene Symbols FANCA
Host Species Rabbit
Immunogen A synthetic peptide corresponding to human FANCA.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2175
Test Specificity This antibody is specific to FANCA.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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