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FANCD2 (phospho S222), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115905 Shop All Abnova Corporation Products
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89-115-905 200 μL
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Catalog No. 89-115-905 Supplier Abnova Corporation Supplier No. PAB12530
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of FANCD2.

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Antigen FANCD2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of FANCD2.
Dilution The optimal working dilution should be determined by the end user.
Formulation No additive
Gene FANCD2
Gene Alias DKFZp762A223/FA-D2/FA4/FACD/FAD/FAD2/FANCD/FLJ23826
Gene Symbols FANCD2
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S222 of human FANCD2.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2177
Test Specificity This antibody is specific to the phosphorylated form of FANCD2.
Target Species Human
Content And Storage Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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