FBLN5 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-131-829	100 μg

Catalog No. 89-131-829 Supplier Abnova Corporation Supplier No. PAB5361

Description

Rabbit polyclonal antibody raised against synthetic peptide of FBLN5.

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq

Specifications

• Antigen: FBLN5
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of FBLN5.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
• Gene: FBLN5
• Gene Alias: ARMD3/DANCE/EVEC/FIBL-5/FLJ90059/UP50
• Gene Symbols: FBLN5
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to C-terminus of human FBLN5.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10516
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only