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FGD1, Rabbit, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against recombinant FGD1.
Supplier: Abnova Corporation PAB20017
Description
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. [provided by RefSeq
Sequence: DSDPGASEPGLLARRGSGSALGGPLDPQFVGPSDTSLGAAPGHRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEGPQRLRSDPSpecifications
FGD1 | |
Polyclonal | |
Rabbit polyclonal antibody raised against recombinant FGD1. | |
In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide) | |
P98174 | |
FGD1 | |
Recombinant protein corresponding to amino acids of human FGD1. | |
100 μL | |
Primary | |
Human | |
Liquid |
Immunofluorescence, Immunohistochemistry (PFA fixed) | |
Unconjugated | |
Immunohistochemistry (1:200-1:500) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user. | |
FGD1 | |
AAS/FGDY/ZFYVE3 | |
Rabbit | |
Antigen affinity purification | |
RUO | |
2245 | |
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
|
IgG |
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