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FGD1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against recombinant FGD1.

Supplier:  Abnova Corporation PAB20017

Catalog No. 89-121-518


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Description

Description

FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. [provided by RefSeq

Sequence: DSDPGASEPGLLARRGSGSALGGPLDPQFVGPSDTSLGAAPGHRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEGPQRLRSDP
Specifications

Specifications

FGD1
Polyclonal
Rabbit polyclonal antibody raised against recombinant FGD1.
In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide)
P98174
FGD1
Recombinant protein corresponding to amino acids of human FGD1.
100 μL
Primary
Human
Liquid
Immunofluorescence, Immunohistochemistry (PFA fixed)
Unconjugated
Immunohistochemistry (1:200-1:500) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user.
FGD1
AAS/FGDY/ZFYVE3
Rabbit
Antigen affinity purification
RUO
2245
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
IgG
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