FGFR3 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-799	400 μL

Catalog No. 89-130-799 Supplier Abnova Corporation Supplier No. PAB3043

Description

Rabbit polyclonal antibody raised against synthetic peptide of FGFR3.

This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq

Specifications

• Antigen: FGFR3
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of FGFR3.
• Dilution: Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: FGFR3
• Gene Accession No.: P22607
• Gene Alias: ACH/CD333/CEK2/HSFGFR3EX/JTK4
• Gene Symbols: FGFR3
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human FGFR3.
• Purification Method: Protein G purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2261
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only