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FLT1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89118388 Shop All Abnova Corporation Products
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89-118-388 50 μg
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Catalog No. 89-118-388 Supplier Abnova Corporation Supplier No. PAB16519
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Description

Rabbit polyclonal antibody raised against synthetic peptide of FLT1.

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia

Specifications

Antigen FLT1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of FLT1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene FLT1
Gene Accession No. P17948
Gene Alias FLT/VEGFR1
Gene Symbols FLT1
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human FLT1.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2321
Test Specificity C-terminal domain of human.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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