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FOLH1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89115349 Shop All Abnova Corporation Products
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89-115-349 100 μL
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Catalog No. 89-115-349 Supplier Abnova Corporation Supplier No. PAB11744

Description

Rabbit polyclonal antibody raised against synthetic peptide of FOLH1.

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq

Specifications

Antigen FOLH1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of FOLH1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene FOLH1
Gene Alias FGCP/FOLH/GCP2/GCPII/NAALAD1/NAALAdase/PSM/PSMA/mGCP
Gene Symbols FOLH1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human FOLH1.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2346
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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