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MilliporeSigma™ Rabbit anti-FOXK2, Polyclonal,

Catalog No. ABE1828MI Shop All MilliporeSigma Products
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ABE1828MI 100 μL
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Catalog No. ABE1828MI Supplier MilliporeSigma™ Supplier No. ABE1828
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Description

Rabbit Polyclonal Antibody

Specifically detects FOXK2 in Human samples, and it is validated for Immunoprecipitation, Western Blotting

Forkhead box protein K2 (UniProt Q01167; also known as FOXK2, Cellular transcription factor ILF-1, Interleukin enhancer-binding factor 1) is encoded by the FOXK2 (also known as ILF, ILF-1, ILF1) gene (Gene ID 3607) in human. FOXK2 is a transcription factor involved in cell proliferation and survival. FOXK1 and FOXK2 belong to the family of Fox transcription factors characterized by the forkhead DNA-binding domains. However, FOXK1 and FOXK2 can be distinguished from other Fox transcription factors by the presence of the forkhead-associated (FHA) domains. FOXK2 interacts with BRCA1-associated protein 1 (BAP1) through the FHA domain in a BAP1 Thr493 phosphorylation-dependent manner. BAP1 in turn recruits HCF-1, thereby forming a ternary complex at the FOXK2 target genes sites, where BAP1 represses FOXK2 target genes expression in a BAP1 DUB activity-dependent manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXK2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Formulation Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No. Q01167
Gene Symbols FOXK2; ILF; ILF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to the C-terminal region of human FOXK2.
Purification Method Unpurified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Epigenetics and Nuclear Function
Primary or Secondary Primary
Gene ID (Entrez) NP_004505
Target Species Human
Content And Storage Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Form Serum
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For Research Use Only

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