Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. ABC937MI

MilliporeSigma™ Rabbit anti-FOXL1, Polyclonal,

Catalog No. ABC937MI Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
ABC937MI 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. ABC937MI Supplier MilliporeSigma™ Supplier No. ABC937
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Specifically detects FOXL1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting

Forkhead box protein L1 (UniProt Q12952; also known as Forkhead-like 11, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7) is encoded by the FOXL1 (also known as FKHL11, FREAC7) gene (Gene ID 2300) in human. FOXL1 protein belongs to the forehead box (Fox) family of transcription factors characterized by a common DNA-binding domain (the forkhead box). FOXL1 is involved in regulating the proliferation of gastrointestinal epithelial cells. Loss of Foxl1 leads to distorted architecture of the stomach and small intestine in mice due to a markedly increased epithelial proliferation. Foxl1 knockout is correlated with an enhanced Wnt/β-catenin pathway activation as evidenced by increased β-catenin nuclear localization. FOXL1 expression is down-regulated in the majority of human clear cell renal cell carcinoma (ccRCC), at both mRNA and protein levels. FOXL1 expression inversely correlates with the aggressive phenotype of ccRCC and the survival outcome of patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXL1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Formulation Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. Q12952
Gene Symbols FOXL1; FKHL11; FREAC7
Host Species Rabbit
Immunogen KLH-conjugated linear peptide corresponding to human FOXL1.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Apoptosis, Cancer
Primary or Secondary Primary
Gene ID (Entrez) NP_005241
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Show More Show Less

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.