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FZD7 Rabbit anti-Bovine, Dog, Hamster, Human, Monkey, Mouse, Rabbit, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89118250 Shop All Abnova Corporation Products
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50 μg
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89-118-250 50 μg
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Catalog No. 89-118-250 Supplier Abnova Corporation Supplier No. PAB16379
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Description

Rabbit polyclonal antibody raised against synthetic peptide of FZD7.

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq]

Specifications

Antigen FZD7
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of FZD7.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene FZD7
Gene Accession No. O75084
Gene Alias FzE3
Gene Symbols FZD7
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to human FZD7.
Purification Method Immunoaffinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8324
Test Specificity C-terminal domain of human.
Target Species Bovine, Canine, Hamster, Human, Monkey, Mouse, Rabbit, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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