GAB2 (phospho Y643), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GAB2.

Supplier:  Abnova Corporation PAB29244

Catalog No. 89-130-680

Description

This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq

Specifications

• Antigen: GAB2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GAB2.
• Formulation: In PBS, pH 7.4 (without mg²⁺ and Ca²⁺), (50% glycerol, 0.02% sodium azide)
• Gene Accession No.: Q9UQC2
• Gene Symbols: GAB2
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y643 of human GAB2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of GAB2 only when phosphorylated at tyrosine 643.
• Content And Storage: Store at -20°C.
  Avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Western Blot (1:500-1000) The optimal working dilution should be determined by the end user.
• Gene: GAB2
• Gene Alias: KIAA0571
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 9846
• Target Species: Human, Mouse, Rat
• Form: Liquid

For Research Use Only