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GAB2 (phospho Y643), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89130680 Shop All Abnova Corporation Products
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89-130-680 100 μL
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Catalog No. 89-130-680 Supplier Abnova Corporation Supplier No. PAB29244
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GAB2.

This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq

Specifications

Antigen GAB2
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GAB2.
Dilution Immunohistochemistry (1:50-1:100) Western Blot (1:500-1000) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (without mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Gene GAB2
Gene Accession No. Q9UQC2
Gene Alias KIAA0571
Gene Symbols GAB2
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y643 of human GAB2.
Purification Method Affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9846
Test Specificity This antibody detects endogenous levels of GAB2 only when phosphorylated at tyrosine 643.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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