GAB2 (phospho Y643), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GAB2.
Supplier: Abnova Corporation PAB29244
This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic phosphopeptide of human GAB2.|
|In PBS, pH 7.4 (without mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)|
|Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y643 of human GAB2.|
|This antibody detects endogenous levels of GAB2 only when phosphorylated at tyrosine 643.|
|Store at -20°C.
Avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (1:50-1:100) Western Blot (1:500-1000) The optimal working dilution should be determined by the end user.|
|Human, Mouse, Rat|
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