GABBR1 Rabbit anti-Bovine, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GABBR1.

Supplier:  Abnova Corporation PAB26219

Catalog No. 89-127-859

Description

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: GABBR1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GABBR1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_001461.1
• Gene Symbols: GABBR1
• Immunogen: A synthetic peptide corresponding to 15 amino acid at N-terminus of human GABBR1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (7-13 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: GABBR1
• Gene Alias: FLJ92613/GABAB(1e)/GABABR1/GABBR1-3/GPRC3A/dJ271M21.1.1/dJ271M21.1.2/hGB1a
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2550
• Target Species: Bovine, Canine, Equine, Hamster, Human, Monkey, Mouse, Pig, Rat
• Form: Liquid

For Research Use Only