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GAD2 Rabbit anti-Rat, Polyclonal Antibody, Abnova™

Catalog No. 89121031 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-121-031 100 μg
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Catalog No. 89-121-031 Supplier Abnova Corporation Supplier No. PAB19504
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Description

Rabbit polyclonal antibody raised against synthetic peptide of GAD2.

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq

Specifications

Antigen GAD2
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of GAD2.
Dilution Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene GAD2
Gene Alias GAD65/MGC161605/MGC161607
Gene Symbols GAD2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids at N-terminus of human GAD2.
Purification Method Immunoaffinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2572
Test Specificity It identical to the related mouse and rat sequence.
Target Species Human
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water and concentration will be 500μ/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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