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GDNF Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Shop All Abnova Corporation ProductsDescription
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
Specifications
Specifications
| Antigen | GDNF |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of GDNF. |
| Dilution | Western Blot (1 ug/mL) Immunohistochemistry (1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal) |
| Gene | GDNF |
| Gene Alias | ATF1/ATF2/HFB1-GDNF |
| Gene Symbols | GDNF |
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For Research Use Only
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