GDNF Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-351	100 μL

Catalog No. 89-114-351 Supplier Abnova Corporation Supplier No. PAB0699

Description

Rabbit polyclonal antibody raised against full-length recombinant GDNF.

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq

Specifications

• Antigen: GDNF
• Applications: Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against full length recombinant GDNF.
• Dilution: Western Blot (1:1000-1:3000) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from PBS
• Gene: GDNF
• Gene Accession No.: P39905
• Gene Alias: ATF1/ATF2/HFB1-GDNF
• Gene Symbols: GDNF
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to full length human GDNF.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2668
• Test Specificity: No cross reativity with NTN has been observed in western blot analysis.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized

For Research Use Only