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GIPR Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89127944 Shop All Abnova Corporation Products
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50 μg
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89-127-944 50 μg
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Catalog No. 89-127-944 Supplier Abnova Corporation Supplier No. PAB26303
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Description

Rabbit polyclonal antibody raised against synthetic peptide of GIPR.

Gastric inhibitory polypeptide (GIP; MIM 137240), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. It is involved in several other facets of the anabolic response.[supplied by OMIM

Specifications

Antigen GIPR
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of GIPR.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8-21 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene GIPR
Gene Accession No. P48546
Gene Alias MGC126722
Gene Symbols GIPR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 19 amino acids at N-terminal extracellular domain of human GIPR.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2696
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GHRHR (100%).
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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