GIPR Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GIPR.

Supplier:  Abnova Corporation PAB26179

Catalog No. 89-127-819

Description

Gastric inhibitory polypeptide (GIP; MIM 137240), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. It is involved in several other facets of the anabolic response.[supplied by OMIM

Specifications

• Antigen: GIPR
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GIPR.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: P48546
• Gene Symbols: GIPR
• Immunogen: A synthetic peptide corresponding to 18 amino acid at cytoplasmic domain of human GIPR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GHRHR (100%), GCGR (61%), GLP2R (61%).
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (32 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: GIPR
• Gene Alias: MGC126722
• Host Species: Rabbit
• Purification Method: Immunoaffinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2696
• Target Species: Human, Monkey
• Form: Liquid

For Research Use Only