Gjb2, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against partial synthetic peptide of human GJB2.

Supplier:  Abnova Corporation PAB7965

Catalog No. 89-133-534

Description

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq

Sequence: MDWGTLQTILGGVNKH

Specifications

• Antigen: Gjb2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against partial synthetic peptide of human GJB2.
• Formulation: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg Thimerosal, 0.05mg NaN3.
• Gene Alias: CX26/DFNA3/DFNB1/HID/KID/NSRD1/PPK
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2706
• Target Species: Human, Mouse, Rat
• Form: Lyophilized

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.1-0.5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: GJB2
• Gene Symbols: GJB2
• Immunogen: A synthetic peptide corresponding to amino acids 1-16 of human GJB2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: The synthetic peptide of this antibody is different from the related mouse and rat sequences by two amino acids.
• Content And Storage: Store at -20°C.
  After reconstitution with 0.2 mL of distilled water and concentration will be 500 ug/mL, store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

For Research Use Only