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GLI2, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89114588 Shop All Abnova Corporation Products
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100 μg
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89-114-588 100 μg
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Catalog No. 89-114-588 Supplier Abnova Corporation Supplier No. PAB10051
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Description

Rabbit polyclonal antibody raised against synthetic peptide of GLI2.

This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq

Specifications

Antigen GLI2
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of GLI2.
Dilution ELISA (1:10,000-1:3,0000) Western Blot (1:500-1:2000) Immunohistochemistry (1:500-1:2000) The optimal working dilution should be determined by the end user.
Formulation In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)
Gene GLI2
Gene Accession No. P10070;NP_084655(isoformalpha)
Gene Alias HPE9/THP1/THP2
Gene Symbols GLI2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids 46-60 of human GLI2.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2736
Test Specificity Expect reactivity with all isoforms of this protein.
Target Species Bovine, Human, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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