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Description
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq
Specifications
Specifications
| Antigen | GM2A |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of GM2A. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/ml) |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | GM2A |
| Gene Accession No. | P17900 |
| Gene Alias | SAP-3 |
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