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Description
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Specifications
Specifications
| Antigen | GPBAR1 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of GPBAR1. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (18 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | GPBAR1 |
| Gene Accession No. | Q8TDU6 |
| Gene Alias | BG37/GPCR/GPCR19/GPR131/M-BAR/MGC40597/TGR5 |
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