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GPBAR1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89129227 Shop All Abnova Corporation Products
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89-129-227 50 μg
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Catalog No. 89-129-227 Supplier Abnova Corporation Supplier No. PAB27710
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Rabbit polyclonal antibody raised against synthetic peptide of GPBAR1.

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq

Specifications

Antigen GPBAR1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of GPBAR1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (18 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene GPBAR1
Gene Accession No. Q8TDU6
Gene Alias BG37/GPCR/GPCR19/GPR131/M-BAR/MGC40597/TGR5
Gene Symbols GPBAR1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acid at cytoplasmic domain of human GPBAR1.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 151306
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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