GPC3, Rabbit, Clone: SP86, Abnova™

Rabbit monoclonal antibody raised against synthetic peptide of GPC3.

Supplier:  Abnova Corporation MAB10040

Catalog No. 89-108-355

Description

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: GPC3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Gene: GPC3
• Gene Symbols: GPC3
• Immunogen: A synthetic peptide corresponding to C-terminus of human GPC3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Clone: SP86
• Description: Rabbit monoclonal antibody raised against synthetic peptide of GPC3.
• Formulation: In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
• Gene Alias: DGSX/OCI-5/SDYS/SGB/SGBS/SGBS1
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2719
• Content And Storage: Store at 4°C. Do not freeze.

For Research Use Only