MilliporeSigma™ Rabbit anti-GRASP65, Polyclonal,

Catalog No.	Quantity
ABS1601MI	100 μL

Catalog No. ABS1601MI Supplier MilliporeSigma™ Supplier No. ABS1601

Description

Rabbit Polyclonal Antibody

Specifically detects GRASP65 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunoprecipitation, Western Blotting

Golgi reassembly stacking protein of 65kDa (also called Golgi reassembly and stacking protein 1 or Golgi peripheral membrane protein p65) is encoded by the Grasp65 or Gorasp65 gene in rat (GRASP65, GORASP1, or GOLPH5 gene in human). It is is a Golgi structural protein and mediates cisternae stacking via self-aggregation as well as interactions with other Golgi membrane-docking proteins, such as GM130. GRASP65 dimers are shown to aggregate in vitro and form extensive trans oligomers, which disaggregate upon phosphorylation by cdc2-cyclin B and polo-like kinases, and re-aggregate upon dephosphorylation (PMID 12839990). Fluorescent imaging studies reveal a dynamic exchange between the membrane-associated and cytosolic GRASP65. (PMID 11706049).

Specifications

• Antigen: GRASP65
• Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Formulation: Rabbit polyclonal serum containing 0.05% sodium azide.
• Gene Accession No.: O35254
• Gene Symbols: Gorasp1; Grasp65
• Host Species: Rabbit
• Immunogen: GST-tagged Recombinant protein corresponding to rat GRASP65.
• Purification Method: Unpurified
• Quantity: 100 μL
• Regulatory Status: RUO
• Research Discipline: Signaling
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_062258
• Target Species: Human, Mouse, Rat
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
• Form: Serum

For Research Use Only