GRB2 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GRB2.

Supplier:  Abnova Corporation PAB4939

Catalog No. 89-131-651

Description

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C. elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: GRB2
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GRB2.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_002077;P62993
• Gene Symbols: GRB2
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding Y209 of human GRB2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:50-100) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
• Gene: GRB2
• Gene Alias: ASH/EGFRBP-GRB2/Grb3-3/MST084/MSTP084
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2885
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only