GRLF1, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GRLF1.

Supplier:  Abnova Corporation PAB17285

Catalog No. 89-118-950

Description

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq

Specifications

• Antigen: GRLF1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GRLF1.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene Accession No.: Q9NRY4
• Gene Symbols: GRLF1
• Immunogen: A synthetic peptide corresponding to internal of human GRLF1.
• Regulatory Status: RUO
• Gene ID (Entrez): 2909
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
• Gene: GRLF1
• Gene Alias: GRF-1/KIAA1722/MGC10745/P190-A/P190A/p190RhoGAP
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of total GRFL1 protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only