GRLF1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-118-950	100 μg

Catalog No. 89-118-950 Supplier Abnova Corporation Supplier No. PAB17285

Description

Rabbit polyclonal antibody raised against synthetic peptide of GRLF1.

The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids. [provided by RefSeq

Specifications

• Antigen: GRLF1
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GRLF1.
• Dilution: Immunohistochemistry (1:50-1:100) ELISA (1:40000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene: GRLF1
• Gene Accession No.: Q9NRY4
• Gene Alias: GRF-1/KIAA1722/MGC10745/P190-A/P190A/p190RhoGAP
• Gene Symbols: GRLF1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to internal of human GRLF1.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2909
• Test Specificity: This antibody detects endogenous levels of total GRFL1 protein.
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only