GRM3 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of GRM3.

Supplier:  Abnova Corporation PAB4440

Catalog No. 89-131-412

Description

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq

Specifications

• Antigen: GRM3
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of GRM3.
• Formulation: In PBS (0.09% sodium azide)
• Gene Accession No.: NP_000831;Q14832
• Gene Symbols: GRM3
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GRM3.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:100-500) The optimal working dilution should be determined by the end user.
• Gene: GRM3
• Gene Alias: GLUR3/GPRC1C/MGLUR3/mGlu3
• Host Species: Rabbit
• Purification Method: Protein A purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2913
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only