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GRPR Rabbit anti-Dog, Horse, Human, Monkey, Pig, Rabbit, Polyclonal Antibody, Abnova™
Shop All Abnova Corporation ProductsDescription
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq
Specifications
Specifications
| Antigen | GRPR |
| Applications | Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of GRPR. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | GRPR |
| Gene Accession No. | P30550 |
| Gene Symbols | GRPR |
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For Research Use Only
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