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GRPR Rabbit anti-Dog, Horse, Human, Monkey, Pig, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89128156 Shop All Abnova Corporation Products
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89-128-156 50 μg
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Catalog No. 89-128-156 Supplier Abnova Corporation Supplier No. PAB26516
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Rabbit polyclonal antibody raised against synthetic peptide of GRPR.

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq

Specifications

Antigen GRPR
Applications Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of GRPR.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene GRPR
Gene Accession No. P30550
Gene Symbols GRPR
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 18 amino acids at 2nd extracellular domain of human GRPR.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2925
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Canine, Equine, Human, Monkey, Pig, Rabbit
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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