MilliporeSigma™ Rabbit anti-Gustducin alpha-3 chain, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABN999

Catalog No. ABN999MI

Description

Specifically detects Gustducin alpha-3 chain in Human, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry

Gustducin alpha-3 chain is a G protein alpha subunit of the taste receptors and it plays a critical role in bitter, sweet and umami (MSG) taste transduction. Gustducin alpha-3 chain operates via the cGMP-phosphodiesterase signaling pathway and is mediated with calcium. Gustducin alpha-3 chain also functions in lumenal sugar sensors in the gut and may modulate the gut capacity to absorb sugars and thus play roles in malabsorption syndromes and diet related disorders including diabetes type II and obesity. Gustducin alpha-3 chain is localized to the cytoplasm and plasmalemmal being a G protein subunit. Gustducin alpha-3 chain is expressed in tastebuds and in the gut in enteroendocrine L cells, and surprisingly in spermatozoa.

Specifications

• Antigen: Gustducin alpha-3 chain
• Classification: Polyclonal
• Gene Accession No.: A8MTJ3
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Rat

• Applications: Immunocytochemistry, Immunohistochemistry
• Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: GNAT3
• Immunogen: KLH-conjugated linear peptide corresponding to human Gustducin alpha-3 chain near the C-terminal.
• Quantity: 100 μg
• Research Discipline: Neuroscience
• Gene ID (Entrez): NP_001095856
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only