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MilliporeSigma™ Rabbit anti-Gustducin alpha-3 chain, Polyclonal,

Catalog No. ABN999MI Shop All MilliporeSigma Products
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ABN999MI 100 μg
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Catalog No. ABN999MI Supplier MilliporeSigma™ Supplier No. ABN999
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Description

Rabbit Polyclonal Antibody

Specifically detects Gustducin alpha-3 chain in Human, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry

Gustducin alpha-3 chain is a G protein alpha subunit of the taste receptors and it plays a critical role in bitter, sweet and umami (MSG) taste transduction. Gustducin alpha-3 chain operates via the cGMP-phosphodiesterase signaling pathway and is mediated with calcium. Gustducin alpha-3 chain also functions in lumenal sugar sensors in the gut and may modulate the gut capacity to absorb sugars and thus play roles in malabsorption syndromes and diet related disorders including diabetes type II and obesity. Gustducin alpha-3 chain is localized to the cytoplasm and plasmalemmal being a G protein subunit. Gustducin alpha-3 chain is expressed in tastebuds and in the gut in enteroendocrine L cells, and surprisingly in spermatozoa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Gustducin alpha-3 chain
Applications Immunocytochemistry, Immunohistochemistry
Classification Polyclonal
Formulation Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. A8MTJ3
Gene Symbols GNAT3
Host Species Rabbit
Immunogen KLH-conjugated linear peptide corresponding to human Gustducin alpha-3 chain near the C-terminal.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Neuroscience
Primary or Secondary Primary
Gene ID (Entrez) NP_001095856
Target Species Human, Rat
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
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For Research Use Only

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