H2AFX (phospho S139), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-127-483	100 μg

Catalog No. 89-127-483 Supplier Abnova Corporation Supplier No. PAB25854

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of H2AFX.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq

Sequence: Q-A-Sp-Q-E

Specifications

• Antigen: H2AFX
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of H2AFX.
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: H2AFX
• Gene Alias: H2A.X/H2A/X/H2AX
• Gene Symbols: H2AFX
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S139 of human H2AFX.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3014
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only