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H2AX, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89113951 Shop All Abnova Corporation Products
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25 μg
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Catalog No. Quantity
89-113-951 25 μg
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Catalog No. 89-113-951 Supplier Abnova Corporation Supplier No. PAB0003

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of Histone H2A.X.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq

Specifications

Antigen H2AX
Applications Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of Histone H2A.X.
Dilution Western Blot (1-2 ug/mL) Immunofluorescence (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 10mM phosphate buffer, 150mM NaCl, pH 7.2 (50% glycerol)
Gene H2AFX
Gene Accession No. NM_002105
Gene Alias H2A.X/H2A/X/H2AX
Gene Symbols H2AFX
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S139 of human Histone H2A.X.
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3014
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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