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HAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89116249 Shop All Abnova Corporation Products
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89-116-249 100 μg
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Catalog No. 89-116-249 Supplier Abnova Corporation Supplier No. PAB12994
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Rabbit polyclonal antibody raised against synthetic peptide of HAP1.

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

Antigen HAP1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of HAP1.
Dilution Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene HAP1
Gene Alias HAP2/HIP5/HLP/hHLP1
Gene Symbols HAP1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to internal region 19 amino acids of human HAP1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9001
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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