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HAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Shop All Abnova Corporation ProductsDescription
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | HAP1 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of HAP1. |
| Dilution | Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | HAP1 |
| Gene Alias | HAP2/HIP5/HLP/hHLP1 |
| Gene Symbols | HAP1 |
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For Research Use Only
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