HAP1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of HAP1.

Supplier:  Abnova Corporation PAB12994

Catalog No. 89-116-249

Description

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Specifications

• Antigen: HAP1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of HAP1.
• Formulation: In PBS (0.02% sodium azide)
• Gene Alias: HAP2/HIP5/HLP/hHLP1
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: HAP1
• Gene Symbols: HAP1
• Immunogen: A synthetic peptide corresponding to internal region 19 amino acids of human HAP1.
• Regulatory Status: RUO
• Gene ID (Entrez): 9001
• Content And Storage: Store at 4°C for three months. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only