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HMGN1, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89114558 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-114-558 100 μg
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Catalog No. 89-114-558 Supplier Abnova Corporation Supplier No. PAB10016
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of HMGN1.

Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM

Specifications

Antigen HMGN1
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of HMGN1.
Dilution ELISA (1:5000-1:25000 Western Blot (1:500-1:2000) Immunohistochemistry (20 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)
Gene HMGN1
Gene Alias FLJ27265/FLJ31471/HMG14/MGC104230/MGC117425
Gene Symbols HMGN1
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S20/S24 of human HMGN1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3150
Test Specificity Reactivity occurs against human HMGN pS20/pS24 proteins and This antibody is specific to the phosphorylated form of the proteins. Reactivity is seen against HMGN1 and HMGN2. HMGN3 is also likely reactive although not tested. Reactivity with non-phosphorylated human HMGNs is minimal by ELISA.
Target Species Bovine, Canine, Chicken, Frog, Human, Mouse, Orangutan, Pig, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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