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HRK Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89126155 Shop All Abnova Corporation Products
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400 μL
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89-126-155 400 μL
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Catalog No. 89-126-155 Supplier Abnova Corporation Supplier No. PAB2444
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Rabbit polyclonal antibody raised against synthetic peptide of HRK.

Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL. [provided by RefSeq

Specifications

Antigen HRK
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of HRK.
Dilution Western Blot (1:1000) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene HRK
Gene Alias DP5/HARAKIRI
Gene Symbols HRK
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to amino acids 30-50 of human HRK.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8739
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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