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HSPA5 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89115277 Shop All Abnova Corporation Products
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89-115-277 100 μL
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Catalog No. 89-115-277 Supplier Abnova Corporation Supplier No. PAB11672

Description

Rabbit polyclonal antibody raised against synthetic peptide of HSPA5.

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM

Specifications

Antigen HSPA5
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of HSPA5.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene HSPA5
Gene Alias BIP/FLJ26106/GRP78/MIF2
Gene Symbols HSPA5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids 24-43 of human HSPA5.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3309
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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